PRGF technology has opened new therapeutic possibilities in various medical areas such as oral implantology, maxillofacial, orthopedic, or arthroscopic surgery, sports medicine, aesthetics, ulcer treatment, ophthalmology, repair of the peripheral nervous system, among others.
Platelets for their ability to secrete a set of proteins at the site of injury contribute the constituents capable of regenerating tissues and remodeling the extracellular matrix. Tissues sensitive to intra-granular growth factors include osteoblastic cells, fibroblasts, smooth muscle cells or tenocytes among others. These observations justify the use of plasma rich in growth factors (PRGF) in different therapeutic situations.
The growth factors have been in the interior of the platelets and are among others:
– PDGF-AB or C: Platelet-derived Growth Factor
– TGF-B1: Transforming Growth Factor
– IGF-I: Insulin Growth Factor
– HGF: Hepatocyte Growth Factor
– EGF: Epidermal Growth Factor
– VEGF: Vascular endothelial growth factor